April | 2013 | Gaia-Health.link

Newly published research by Keele Conference scientists shows that aluminum adjuvant in vaccines transfers to the brain. They have documented the path from injection site to the brain, and that once in the brain, it persists. Newborns, the elderly, and people with a certain genetic variation are particularly at risk.

by Heidi Stevenson

A new study adds a major link in the association of aluminum adjuvants in vaccines with neurological disorders. It demonstrates the pathway along which aluminum in vaccine adjuvants is transferred from the injection site to the brain, where it persists indefinitely. They have also identified a likely carrier and a means by which the process occurs.

The study is exhaustive, eliminating a wide array of options that might mitigate against their findings. They also focused on two groups to determine if their findings indicate that they’re at particular risk. They include newborns and people with a certain genetic variant. On top of that, the elderly may be at significantly higher risk for aluminum adjuvant-induced neurotoxic harm.

Please note that variant does not mean defective! We all have genes that are not like those of the majority. That does not indicate a defect, only a distinction. Viva la difference!

Reason for the Study

Nanoparticles are not as new in medicine as generally believed. The study states:

The use of nanomaterials in humans is not as contemporary as is recently portrayed. For decades, alum, a nanocrystalline compound formed of aluminum oxyhydroxide, has been the most commonly used adjuvant in vaccines.

In macrophagic myofasciitis (MMF), “alum-loaded macrophages [are] typically detected at sites of previous injections (up to >12 years later), resulting in a specific granuloma called macrophagic myofasciitis or MMF.” *

CCL2 is a cytokine that recruits monocytes, memory T cells, and dendritic cells to sites of inflammation. Earlier work has shown that 252 ASIA patients had an increase in circulating CCL2, along with a variation in the CCL2 gene. It’s also known that:

Danger signals from the CCL2 cytokine draw monocytes, which causes them to convert to macrophages before migrating to lymph nodes.
Dendritic cells (DCs) transfer antigens to a large network of distant dendritic cells, also known as antigen-presenting cells (APCs).
Alum injections are known to incite “significant changes linked to activation of the innate immune system in distant organs”.

These facts resulted in this study to detemine whether injected nanomaterials, most particularly alum, could be moved to distant organs through phagocytosis and CCL2 signaling.

The Experiments

Experiments were done on laboratory mice. A fluorescent surrogate for alum particles, fluorescent latex beads (FLBs), was used to assess movement and distribution of intramuscularly injected materials. Morin stain and particle induced X-ray emission (PIXE) were used to assess movement of alum hybrids, Al-Rho, which match the particle size of injected adjuvant aluminum. Using graphics from the study, I will attempt to explain what was done, though not all aspects of the study will be covered.

Granulomas

Standard C57BL/6 lab mice were injected in the tibialis anterior muscle (equivalent to a calf muscle in humans) with an alum-containing vaccine at a dose equivalent to that given to humans, with the amount calculated by an FDA standard. As is intended with an adjuvant, an intense localized inflammation ensued, which lasted until day 4 post-injection, when it stabilized. The local aluminum concentration decreased rapidly until day 4, remaining stable until day 21.

Aluminum-Laced Granuloma

Aluminum-loaded macrophages were found encased in granulomas from day 4 post-injection, as shown in this image. The left-hand image shows a photo of a granuloma, and the right-hand image is a PIXE graphic demonstrating the high aluminum load. (Yellow shows the greatest load.)

Signs of aluminum were found in the spleens and brains of these mice, as shown in these graphics:

Aluminum-Laced Spleen and Brain

Photographic images show spleen (left) and brain (right) tissues, with areas of PIXE imagery indicated with bright pink squares. The PIXE images showing aluminum loading are on the right side of each photo.

Aluminum Loading of Brain, Graphed Days 21 through 365, Plus Unvaccinated Controls

The graph on the left shows the percent of areas in the brains found to have aluminum spots. Notice the small number in unvaccinated mice. The numbers shown on days 21 and 365, one year post-vaccination, demonstrate that the aluminum does not dissipate. (The authors believe that the bar for day 180 is an anomaly, caused by either “interindividual variations in aluminum handling or to sampling problems related to variable proportions of grey and white matter in the randomly scanned areas”.

The aluminum that makes its way to the brain is persistent.

Movement of Alum Surrogates

FLB Movement by Macrophages, Hour 1 and Day 4

The image to the right shows the movement of FLBs by macrophages from the injection site to interstitial spaces in the muscle around it. Notice the bright red slash in the image to the left showing the fluorescing surrogates for alum, FLBs (fluorescent latex beads) one hour after injection. The right-hand image shows how they’ve been dispersed by macrophages four days later.

FLB Movement to Lymph Nodes, Hour 1 through Day 21

The image to the left is a graph of the number of cells loaded with FLBs (surrogate alum) found in popliteal (knee area) lymph nodes (P-DLN) and inguinal (groin) lymph nodes (I-DLN) at one hour, day 4, and day 21. Notice that movement of FLBs to lymph nodes is dramatic by day 4. Other images (not shown) document that this movement can be accounted for by inflammatory dendritic cells and macrophages that are derived from monocytes.

Another related part of this section of the experiment utilized injection of a compound known to inhibit FLB movement by phagocytes to popliteal lymph nodes. At day 4 movement to popliteal lymph nodes was down by 32%, and to inguinal lymph nodes by 69%. This treatment resulted in significant reduction of FLB in lymph nodes, further confirming that macrophages are the primary means of transportation to lymph nodes.

Graphs-of-Aluminum-found-in-Spleen-and-Blood

Graphs of FLBs found in Spleen and Blood

After moving to lymph nodes, the FLB alum surrogates moved to the spleen, as shown in the image to the right. The left-hand graph shows the number of FLBs in the spleen peaking at day 21 and decreasing to a little over half that number on day 90. Compare this with the previous graph, which shows FLBs leaving the lymph nodes between days 4 and 21. This increase in FLBs in the spleen between these same dates indicates that they’re moving from lymph nodes to the spleen.

The question then is: How does that happen? There is no connection between lymph nodes and the spleen. However, if you look at the graph on the right, you can see that FLBs are found in the blood, too. The authors surmise that the FLBs must travel in macrophages through the thoracic duct, the largest lymph vessel, which releases most of the body’s lymph into the blood system. Thus, macrophages carrying the alum-surrogate FLBs are transported from lymph nodes into the blood system, and then arrive in the spleen.

Graph of FLB Movement into Brain

The authors wrote, “Cerebral translocation of FLBs was delayed but relentless until the d90 endpoint in C57 mice,” and the graph to the left shows it. Only a small amount of the alum surrogate injected into the standard C57 lab mice reached the brain on day 4, but you can readily see how the pace picks up by day 21, and more than doubles again by day 90, the endpoint of the study on C57 mice.

The CX3CR1^GFP/+mice, indicated by the white bars, have an inserted gene that allows visualization of the microglia, which are a particular kind of macrophage found in the brain and spinal cord. As you can see, the FLBs were still increasing on day 180, the study’s endpoint for these mice.

FLBs in the Brainstem

The image to the right shows FLBs in the brainstem of a CX3CR1^GFP/+mouse. The inset is a photo of a stained slice of brain with their locations indicated by dots. The larger image is of an unstained section on day 21 showing the FLBs located mostly just under the pia membrane, i.e., on the surface of the brainstem.

Preventing FLBs from Transporting to Organs

Effect of I.V. Injections

Some C57 mice were given the FLB injection intravenously into the tail, rather than into the tibial anterior leg muscle. The result is shown in the graph on the left. Notice that hardly any FLBs ended up in the brain by either day 21 or 90. Clearly, little, if any, immune response resulting in macrophages engulfing FLBs is triggered by an intravenous injection.

Percent of FLB-Loaded Cells After Lymph Node Ablation

After ablating (destroying) popliteal and inguinal lymph nodes, the number of FLBs reaching the blood, spleen, and brain was reduced by 60-80%. The graph to the left shows the percentage of FLBs remaining compared to controls. The number that reached the spleen was only about 20% and the number reaching the brain was about 40%. This indicates that movement of FLBs by macrophages to local lymph nodes is part of the process for movement of most FLBs—and by analogy, most alum—from injection site to organs, including the brain.

Blood-Brain Barrier

FLBs with a Weak Blood-Brain-Barrier

One of the concerns in clinical procedures involving toxic elements on newborn babies is their weak blood-brain barrier. Mice with a leaky blood-brain barrier, called mdx, were used to see what happens in this situation. The graph to the right shows that, by day 21 the number of FLBs reaching the brain of an mdx mouse with a leaky blood-brain barrier is significantly greater than in a normal C57 mouse, and that this remains a problem over time.

Images from the muscles, spleen, and brain chimeric (genetically engineered) mice with a green fluorescing protein confirmed these findings.

Morin Stains Showing Al-Rho Particles

Confirmation: FLBs Correlate with Alum Adjuvant

The Morin stain for aluminum showed “Al-Rho particles were avidly phagocytosed after i.m. injection and formed intracellular agglomerates similar in size to the vaccine adjuvant”, as can be seen by the clusters in the “Vaccine” and “Al-Rho” images to the left. These images are similar to the first image of an aluminum-induced granuloma shown above.

The graphs below show Al-Rho movement from lymph nodes to spleen, and spleen to brain:

Al-Rho Movement to Lymph Nodes, Spleen, and Brain

The Al-Rho nanohybrid surrogates for alum showed up prominently in the popliteal and inguinal lymph nodes, which are nearest to the injection site, by day 4, as shown in the left-hand graph. Most have moved by day 21, showing up in the spleen, as you can see by the middle graph. By day 90, you can see that a significant number of Al-Rho have left the spleen. However, from the graph on the right, you can see that they’ve been moving from the spleen to the brain. The movement is strikingly similar to that of the FLBs.

Effect of CCL2 Cytokines in Alum Distribution

The CCL2 cytokine is suspected to be at the center of some ASIA disorders because research has shown that ASIA patients have high amounts in their blood, along with a genetic variant related to CCL2. Mice bred to be deficient in the CCL2 cytokine were used to see what effect they have on distribution of the alum surrogate, Al-Rho, to lymph nodes and organs.

Movement of Al-Rho in CCL2-Deficient Mice

In the left-hand graph of the image to the right, you can see that there is significantly less movement of Al-Rho from the site of an intramuscular injection to organs. Compared with controls, 65% the amount of Al-Rho is found in the nearest lymph node at day 4, and even less, 34%, gets to the inguinal lymph node. On day 21, only 15% as much is found in the blood, 29% in the spleen, and only 18% as much Al-Rho is found in the brains of CCL2-deficient mice compared to controls.

The graph to the right of “CCL2 Deficient Mice” shows the amount of Al-Rho found in the same kind of CCL2-deficient mice after they’ve been injected with rCCL2, a recombinant form of CCL2 that was used because no other version is available. The results are dramatically different. First, note that the y-axis scale is dramatically different, running up to 600%, instead of only 80%. By day 21, the rCCL2 injections increased distribution of Al-Rho to the blood by 274%, the spleen by 180%, and the brain by 341% as compared to controls.

These experiments, along with others not described here, document that more CCL2 cytokines—which draw monocytes and dendritic cells to the site of inflammation—than normal are directly associated with the distribution of alum to the brain.

Implications

This study has demonstrated that aluminum adjuvant particles can be transported to the brain through CCL2 signaling that brings monocytes to the site of vaccine administration. The route is shown to be:

First to the nearest lymph nodes.
Through the lymph system’s thoracic duct.
Through the thoracic duct into the bloodstream.
Through the blood to the spleen and possibly partially directly to the brain.
From the spleen to the brain.

This process appears to occur in all mice, though at a slow rate. However, in mice with high levels of CCL2 cytokines, the process is speeded up dramatically. The study also documented that an inefficient blood-brain barrier, as is found in the youngest babies, allows significantly more alum through to the brain.

The toxic potential of aluminum is high. This study has demonstrated that injecting alum adjuvants with vaccines results in transferrence to the brain, where it persists. Most people have a high tolerance to alum. However, there are limits in anyone. In the case of people with high levels of CCL2—such as those with a genetic variant leading to high CCL2 levels, as found in ASIA patients—even small amounts of injected alum can be disastrous.

Consideration needs also to be given to the association of aluminum in the brain with Alzheimer’s disease, which is afflicting an accelerating percentage of people as they age.

As the study’s authors point out:

It is likely that good tolerance to alum may be challenged by a variety of factors including overimmunization, BBB immaturity, individual susceptibility factors, and aging that may be associated with both subtle BBB [blood-brain barrier] alterations and a progressiveincrease of CCL2 production.

With the rapidly increasing number of vaccinations recommended, and even mandated, in schedules, along with the increasing number of people suffering from chronic neurological and autoimmune disorders, surely it’s past time to sound the alarm. At the very least, serious research to investigate these risks must be launched.

The researchers involved with the Keele Conference are doing valuable research aimed at identifying and mitigating these risks. It’s long past time for the agencies supposedly concerned with public health to follow these leaders of science.

Three of the study’s authors, Christopher Exley, Romain Gherardi, and François-Jérôme Authier, attended the 10^thKeele Conference titled, “Illuminating and Elucidating Aluminium’s Exposome: From Geochemistry to Neurochemistry, From Microbe to Man”:

Dr. Exley was the conference administrator and has published a large number of studies on the topic, not to mention being involved in several of the studies and references of this conference.
Dr. Gherardi presented his latest work on macrophagic myofasciitis (MMF), a new vaccine-associated disease, indicating that the cytokine CCL2 is not simply a biomarker of MMF inflammation, but is also associated with its pathophysiology. He suggested that CCL2 should be investigated in relation to other autoimmune/inflammatory syndromes (ASIA).
Dr. Authier reported on a new non-invasive method to diagnose MMF, which has hitherto been diagnosable only via muscle biopsy. He also suggested that MMF is probably more prevalent than currently realized.

* Unattributed quotations are from the study.

Source:

Slow CCL2-dependent translocation of biopersistent particles from muscle to brain, Biomed Central Medicine; Zakir Khan, Christophe Combadière, François-Jérôme Authier, Valérie Itier, François Lux, Christopher Exley, Meriem Mahrouf-Yorgov, Xavier Decrouy, Philippe Moretto, Olivier Tillement, Romain K Gherardi, and Josette Cadusseau; doi:10.1186/1741-7015-11-99

Tagged adjuvant brain, adjuvant spleen, al-rho, alum adjuvant, alum brain, alum vaccine adjuvant, aluminum brain, asia vaccine, biomed central, ccl2, ccl2 alum, ccl2 cytokine, ccl2 vaccines, dendrite, dendrite vaccine, flb, fluorescent latex bead, granuloma adjuvant, granuloma alum, granuloma vaccine, macrophage, macrophage vaccine, monocyte, monocyte vaccine, nano adjuvant, nano aluminum, nano vaccine, phagocytosis, Slow CCL2-dependent translocation of biopersistent particles from muscle to brain, surrogate adjuvant, vaccine adjuvant

Organic food isn’t cheap, and the real thing never will be. The concept of mass-produced organics is fraudulent. It runs counter to both the ethos & reality. They cannot be produced by Agribusiness-style farmers who keep producing the same crop year-on-year. As long as food is treated as a commodity, then we have degraded the basic substance of our bodies and minds.

by Heidi Stevenson

On top of the recent horsemeat scandal, we now have human DNA found in meat produced by Agribusiness. Lest we forget, the horsemeat scandal started in exactly the same way. First, it was announced that traces of horsemeat DNA had been found in some beef products. Then, we heard about how it was actually more than DNA, but significant percentages. Finally, we learned that some “beef” products had no beef at all—they were 100% horsemeat!

Of course, we were informed that there was no need to worry about it. Government agencies assured us that it was perfectly safe.

Now, though, we’re learning that human DNA is being found in South African Agribusiness foods. Naturally, no one should worry … but it shouldn’t be surprising, because, after all, humans do cut meat up and … well, sometimes they injure themselves. That does, though, beg the question: Why aren’t the factory lines stopped and the contamination from human blood—and even body parts—from such accidents removed?

And that, of course, is the rub. It won’t happen because time is money, and so is that human DNA contaminated meat. Surely you don’t expect anything to stand in the way of Agribusiness profits, do you?

There’s a very important lesson to be learned from all this. Real food—organic food—is not produced by Agribusiness. Real food cannot be produced by “economies of scale”, which is the mantra of Big Business.

Economies of Scale

Economy of scale is the idea that prices can be cut if products are produced in larger and larger quantities. There’s truth to that, but the biggest benefactor is corporations, which are focused on profits over and above everything else. Lest anyone question that statement, it must be noted that a corporation’s first duty—by law!—is to the investors. Corporations are required to place profits over any other concerns. Everything else is treated as a means to profit, not as holding any inherent value.

The reason we’re seeing so many mass outbreaks of food poisoning and contamination is the food industry itself. The prevention efforts are utterly misguided. They focus on control and sterility—not just sensible cleanliness.

Foods are routinely being sterilized now. This does nothing to prevent the problem and destroys much of the nutritional value, while also harming the food’s quality, even to the point of creating toxins, which are then eaten by people.

Controls are being put into place, such as tagging every single animal and recording every detail of their movement. These extra requirements are driving the small farmer—the real farmer—out of business. That, of course, leaves ever more of the food business in the hands of Agribusiness. And that leads to ever more “economies of scale”, with ever more pressure on the producers and workers to produce more and faster.

That pressure results in accidents leading to human flesh in meat and ever-more reason for unscrupulous operators to cut corners, which is the reason behind the horsemeat scandal. It also results in under-payment and mistreatment of workers, further degrading society.

Food as a Commodity

Treating food as nothing but a commodity destroys it. Shortcuts will continue to be used to avoid the inherent problems of mass production. Methods are put in place to disguise the harm. The fact that most so-called fresh vegetables in supermarkets—including ones defined as “organic”—are anything but fresh is ignored:

They’ve often traveled thousands of miles.
They’ve spent who-knows-how-much time just sitting in gas storage, which makes them look like they’re still fresh, but does absolutely nothing to stop the deterioration of nutrients, resulting in “foods” that still have calories, but are becoming devoid of nutritional value.
They’re disguised to look fresh and lovely. They’re waxed and dyed.
They’re being irradiated to give an appearance of freshness—but that process also destroys nutrients.
They’re grown on depleted soils, resulting in far lower nutrient levels.
They’re sprayed with pesticides—and don’t think that foods labeled organic are necessarily free of them. Rules and regulations often allow the use of pesticides on organic crops in some circumstances.

Beyond those problems, you can never know if fruits and vegetables have been contaminated by the effluent from modern CAFOs—concentrated animal feed operations. These examples of institutionalized cruelty result in turning healthy meats into the equivalent of poisons:

CAFO animals are fed unnatural diets to fatten them up. This results in animals being in constant pain as their systems struggle to digest what’s unnatural to them. It does not result in normal healthy meat.
They are highly stressed living in horrific concentrations, with little room to move and no natural interaction with their species—so you eat their stress hormones.
They often live in their own filth. You can imagine the implications of that on their health and yours.
They’re given drugs, including both antibiotics and ractopamine, to cause both rapid and massive growth. Ractopamine is a poison, and it puts animals in pain—which shouldn’t be surprising if you experienced growth pain as an adolescent.
These problems result in very sick animals prone to disease. Therefore, they are massively and routinely given antibiotics to mask their ill health.
Some of these methods are used in so-called “organic” and “free range” animals. The truth is that most so-called free range animals raised in CAFOs never go outside. The term organic does not mean free range, and in some instances doesn’t even mean antibiotic-free.

All of the focus on controls and sterilization completely misses the point. We literally are what we eat. As long as food is treated as a commodity, then we have degraded the basic substance of our bodies and minds.

Organic Food

Organic food—real organic food, not the faux stuff produced by Agribusiness and passed by the USDA—is not mass produced. It’s not produced on large-scale farms. It’s not produced by corporations.

Genuine organic food is produced in small quantities. It’s produced on farms that rotate their crops. It’s produced by natural means—and yes, sometimes that results in crop failures, though the oft-concealed reality is that the same thing happens to Agribusiness crops, though on a much larger scale. Organic crops come from seeds with a wide range of variations; there were once nearly-countless varieties of virtually every food, including meats. Organic food is not doctored to be prettier so you’ll buy it. Animals raised for organic meat are not routinely treated with antibiotics or other drugs, fed unnatural foods, or forced to live in misery. Organic meat, unlike the stuff that’s sold in supermarkets, including most of what’s labeled as organic or free range, is healthy.

The term organic has been compromised. What you find labeled as organic food in supermarkets has usually been gas stored and subjected to a range of mass production techniques. What we must come to appreciate is that organic food is not cheap food. If we go along with large-scale operations that sell stuff as organic, but allows corner-cutting, then we are adding to our own misery. The term organic, as defined by governments—and many other agencies—has been compromised. The USDA allows carageenan, a chemical that causes harmful gastrointestinal effects, to be added to foods with the organic label. In England, pharmaceutical drugs can be, and often are used in animals raised for food—and the number of allowable vaccinations is unlimited.

Obviously, the only way you can be sure of your food supply is by knowing the source. Those pretty, feel-good images on so-called organic foods found in supermarkets are nothing but marketing. They don’t present the reality. If you want real organic food, you must take responsibility for it yourself. You can’t buy it at a discount rate. It isn’t available from marketers saying that they bring “economies of scale” to the business. Economies of scale are the heart and soul of Agribusiness, but they’re anathema to organics.

At some point, people need to understand that using the tools of Agribusiness in organic foods is dishonest. Ultimately, if price becomes the sole issue on which people purchase organic food, then it will go the way of conventionally-grown food stuff. Indeed, that process has already started.

Tagged agribusiness, agribusiness economies of scale, conventional food, economies of scale, food as commodity, mass-produced organic, organic, organic antibiotics, organic food, organic gas storage, organic meat, organic vegetables

A study shows that children with environmentally-induced genetic changes are more likely to have regress into autism. But that has nothing to do with whether autism is inherited. That’s why such research is an utter waste of resources. This is nothing but a sideshow intended to redirect attention away from the probable real cause: vaccines.

by Heidi Stevenson

Autism Awareness month, which is on now, brings out some of the worst junk science on the issue. The worst of all is the genetics research, which is now the beneficiary of millions of dollars, pounds, euros—pick your currency. And this time around is no different. We now have a study stating that autism is linked to changes in a region noted for genome instability.

So what? Seriously, so what? This does not help identify the cause of autism. Every bad health condition can be associated with genetics. The fact is that we’re all different, and part of that difference is our genetic basis. Our genes determine hair color, eye color, skin color, height, body type, voice range, and a huge array of characteristics that help to describe us. It also means that each of us is different in terms of inherent strengths and weaknesses—and that includes susceptibility to diseases of all types.

During an epidemic, some people exposed to the pathogen do not succumb. Why? Part of it is good health … but part of it is also innate susceptibility. That’s even more true when it comes to the modern plague of chronic disorders, including autism.

The Study

The study, “Global increases in both common and rare copy number load associated with autism”^[1] found that 5-10% of autistic children have a change in a region of the genome noted for instability. That means an epigenetic, environmentally induced, change in the genome has happened.

It says absolutely nothing about what has caused the changes!

The study did not find that these changes in that part of the genome exist only in children with autism. It found these changes in children without autism, too. In fact, even when the worst autism cases are taken into account, the percentage of children with autism who have the gene is only about double those who don’t have autism. Look at these graphs to see:

Graph of genetic changes These graphs display the relative number of duplication (left-hand graph) and deletion (right-hand graph) changes occurred in their study. They showed that, in terms of duplications of base pairs, the non-autistic control group (NIMH controls) were at a rate more than one-third of the most severe autism cases (ID/MCA), and only slightly below the average autism group (SSC autism). In terms of deletions of base pairs, the differences were even less.

So, what they’ve shown is only that autistic children are more likely to have an environmentally-induced genetic variation at one point in the genome—and that only 5-10% of autistic children have that kind of genetic variation in that location. So why don’t the other children with that variation also suffer? That isn’t answered.

And that’s the point. This study in no sense demonstrates that there is any genetic cause for autism. They’ve demonstrated only that changes in genetic structure known to be caused by environmental effects result in a child to be 5-10% more likely to develop autism. It says absolutely nothing about what environmental stimulus does it.

Why Do Such a Study?

Is there anything technically wrong with this study? In fact, it’s probably quite good. However, it should not have been done. The expenditure of money on a study that cannot possibly help identify the cause of autism is an utter waste of resources in an era when 1 out of 50 children is regressing into autism. It’s a travesty.

Obviously, there is no truth to the claim that vaccines have nothing to do with autism:

It’s been acknowledged in the US vaccination court and in Italy’s court system.
There’s a growing body of scientific evidence demonstrating a strong association between vaccines and autism.
Strong evidence that ties the increase in autism rates to the increasing number of vaccines given to children exists.
Modern countries with the highest child mortality rates have the highest rates of vaccinations.
Thousands, perhaps millions, of parents attest to the evidence of seeing their children regress following vaccinations. That’s more than anecdotal, it’s a mass of evidence.

In the face of the evidence demonstrating a link between autism and vaccines, there is simply no excuse for evasion of the study that can show the truth. Simply compare the rates of autism between vaccinated and unvaccinated children.

But that’s precisely what the CDC and all other agencies that are supposedly concerned with autism flatly refuse to do. And that’s positively criminal.

Until such a study is done, there can be no proof that vaccines are innocent. Of course, the money behind vaccines is enormous, and it’s being spent to assure that nothing can get in the way of Big Pharma’s and doctor’s profits. Nothing is allowed to stand between corporate profits … including the lives of our children

Sources:

Global increases in both common and rare copy number load associated with autism, Human Molecular Genetics; S. Girirajan, R. L. Johnson, et al; DOI: 10.1093/hmg/ddt136
Relative Burden of Large CNVs on a Range of Neurodevelopmental Phenotypes, PLoS; Santhosh Girirajan, Zoran Brkanac, et al; doi:10.1371/journal.pgen.1002334
Autism Linked to Increased Genetic Change in Regions of Genome Stability

Tagged autism, autism cause, autism genetics, autism regression, autism science, autism study vaccinated vs unvaccinated, autism vaccines, big pharma, cause of autism, genetics autism cause, genetics doesn’t cause autism, genetics science, genetics science autism, Human Molecular Genetics, Human Molecular Genetics autism, junk science, pseudoscience, science, vaccine, vaccines

Petroleum forms the basis of one of the most devastating adjuvants in existence. Historically, it was considered too dangerous for use in vaccines, but it’s making a comeback in this new age of recombinant DNA vaccine development. Of course, the public relations mantra is that it’s safe—so why is it kept quiet?

by Heidi Stevenson

The current hype in a new vaccine against foot-and-mouth disease is all about how the new ones are safer. But are they? The clue is in what isn’t discussed: the adjuvants. PLoS reports that a UK government and Big Pharma funded study has found a new approach, using recombinant DNA technology, to create empty capsids, that is, empty virus protein shells, to use as antigens against foot-and-mouth disease.^[1]The hollow antigens would be grown inside insects.

Antigens and Adjuvants

Only the surface of an antigen is required to show the immune system how to create antibodies. This method of vaccine development makes it impossible to spread the infection, since none of the active part of a virus is included. It also means that vaccine antigens can be made both rapidly and relatively cheaply.

There’s one big disadvantage, though. The immune system isn’t all that dumb. It does appear to be capable of distinguishing between genuine and fake threats. So, something is needed to trick it.

These synthetic antigens aren’t able to trigger much of an immune response when injected. Therefore, an adjuvant is required, and it must be particularly strong for the vaccine to trigger a strong enough immune response to result in antibodies to the antigen.

The problem is that all adjuvants are, by definition, toxic. Their function is to fire up the body’s immune system. Try this analogy:

Photo by Njambi Ndiba

Picture a tiger in a cage, one that’s well-fed, content, and has spent his entire life in it. The audience wants a show and the zookeepers want to give it. So they toss some chicken skins in his cage, hoping he’ll get excited, and start growling and shredding the skins.

But they fail to interest him. He’s used to a certain amount of aggravation. Kids hooting don’t faze him at all. People tossing odds and ends of things into his cage … oh well, he’s gotten used to it. So, the zookeepers—having no moral sense about the animals under their care—spray the tiger with pepper spray.

Now, that gets him riled up! He roars and looks for something to attack. And what does he find? Those chicken skins. So he puts on a great show, fussing and fuming and shredding those skins to bits.

The pepper spray is equivalent to a vaccine adjuvant. Had the zookeepers tossed live chickens into the cage, that tiger would have gone after them and put on a great show. But chicken skins just weren’t interesting enough.

Empty capsids are to the immune system much like chicken skins are to that tiger. You can inject and inject them, but the immune system won’t care. So, you need to toss something really aggravating into the mix. That something is a strong adjuvant.

And that’s exactly what this vaccine will require. According to the PLoS study, the adjuvant proposed for use is called Seppic 206B. The manufacturer’s website defines it as:

Ready-to-use oily vaccine adjuvant for water-in-oil-in-water (W/O/W) emulsion

Based on high-grade injectable mineral oil^[2]

Mineral oil is made from petroleum. It is the same oil that’s the basis of Freund’s adjuvant, which is used to create autoimmune disorders in laboratory animals by injection. Shortly after discovery, they were banned from use in humans because they were recognized as too dangerous.

And this is what is now being praised as safe. The publicity gives the impression that the vaccine itself is safe, but careful reading shows that the safety element is associated only with the manufacturing process—the fact that no live virus is used, so there’s no chance of accidental infection or escape. It has nothing to do with the safety of injecting it.

Animal Abuse

The initial goal of this new technology is to produce a new vaccine against hoof-and-mouth disease so that it can be used on a mass scale in livestock. The plan, obviously, is to use the same kind of adjuvant that’s sold to science labs around the world for the purpose of creating severe autoimmune disorders like rheumatoid arthritis in lab animals.

As long as their pain from these horrible diseases isn’t obvious, who’s going to know how the animals suffer? You know that no one’s going to be watching to see if they’re harmed. One of the most difficult things to deal with in an autoimmune disorder is that they often don’t show on the outside. Sufferers of myalgic encephalitis (chronic fatigue syndrome) have routinely been accused of malingering simply because their misery showed only on their faces.

In the case of animals raised for food … well, these won’t be healthy beasts, and it isn’t healthy to eat meat from sick animals. In the case of animals raised for dairy, their milk would likely contain the inflammatory agents that result from an autoimmune disorder. You have to wonder at that. Will they redefine the “safe” levels of inflammation markers in milk, since they usually won’t find pathogens associated with it? Or just pasteurize it more? That process already exists in long shelf life milk that doesn’t require refrigeration.

The Real Goal

The study’s authors state:

… the approach we have demonstrated here may be applicable across a wide range of human and animal picornaviruses, including polioviruses and coxsackieviruses.^[1] [Emphasis mine.]

It is not the intention to use this technology only on animals. The goal is to develop vaccines for humans. These vaccines, by their very nature, will require very strong adjuvants.

The nature of any adjuvant is to be toxic. That’s what makes them work. The weaker the antigen, the stronger the adjuvant must be. The new technology utilizes an adjuvant that’s known to be extremely toxic, so much so that it’s used to produce autoimmune disorders in lab animals.

This mineral oil adjuvant is already in use on farm animals. Aside from the incredible abuse that factory farming heaps on those poor beasts, how many of them live in constant pain simply because of the vaccinations given? But these animals are kept out of sight—and out of sight does tend to mean out of mind. After all, most people still buy their meat in supermarkets, which are the mainstay of these industrialized farms.

The real goal is to bring these mineral oil based adjuvants to humans. These, and others like squalene, which is responsible for the recent mass outbreak of debilitating narcolepsy from the swine flu vaccine, will be used so that Big Pharma can produce vaccines quickly and cheaply.

We’re living in an era of mass vaccination. The results are showing up in our children. The average child is now sick. The countries with the highest vaccination rates have the highest child mortality rates. Rather than do legitimate studies to identify the reasons for it, we see junk study after pseudo study trying to convince us that vaccines are just fine. Meanwhile, even with strong evidence of vaccination harm, the push is on to produce more and more, faster and faster.

And the lives that are devasted? Oh well, that’s too bad … and anyway, it’s mere coincidence when a child gets autism or arthritis or asthma or bullous pemphigoid or cancer or diabetes or eczema or …

Note: Study funders were the Wellcome Trust, a foundation started by the company now called GlaxoSmithKline; DEFRA, UK agency that controls animal vaccination and promotes it; Medical Research Council, an agency funded by the taxpayers.

Five of the nine researchers have deep ties to the vaccine industry, including a lead researcher who’s a Jenner Investigator, two students supported by the Wellcome Trust, and two supported by the Medical Research Council.

Sources:

Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen. PLoS Pathog; Porta C, Kotecha A, Burman A, Jackson T, Ren J, et al. (2013) 9(3): e1003255. doi:10.1371/journal.ppat.1003255
Montanide ISA 206 VG
New foot-and-mouth vaccine is safer and cheaper to produce
New hope for safer, more stable foot and mouth disease vaccine
Scientists develop new foot and mouth vaccine
Montanide ISA 206 VG
Aspects of the role of mineral oil as immunological adjuvants in rheumatoid arthritis
Autoimmunity induced by adjuvant hydrocarbon oil components of vaccine

Tagged adjuvant toxic, chronic disease vaccines, empty capsids vaccine, freund’s adjuvant, immune system adjuvants, immune system antibodies, immune system antigens, immune system vaccines, junk science, junk study, mineral oil adjuvant, mineral oil petroleum, oil adjuvant, petroleum adjuvant, pseudo study, pseudo-science, pseudoscience, recombinant dna technology, science, vaccine, vaccine adjuvant, vaccines

There seems to be no end to medical science’s hubris. Now, they’ve got the basic nature of every newborn baby’s immune system in the crosshairs. It doesn’t work the way they want it to, so they declare it to be defective … and then set about finding a method to ‘fix’ it. VTX-294 may be the scariest vaccine adjuvant they’ve yet devised.

by Heidi Stevenson

In a blatant display of hubris, medical science has decided that there’s something inherently wrong with newborn babies’ immune systems. Since they don’t naturally react to invaders by developing antibodies, they assume that it’s an inherent flaw, one that needs to be fixed by their science. And now, they believe that they’ve found a means to overcome the natural development of newborns’ immune systems with a new adjuvant called VTX-294.

A vaccine adjuvant is any substance that increases the immune system’s response to an antigen. An infant’s immune system functions differently from an adult’s. This is called a flaw by those who promote vaccines. So they’re hailing the discovery by researchers at Boston Children’s Hospital,^[1] who have discovered that infants’ white blood cells do respond strongly to at least one synthetic compound called VTX-294. It results in triggering tumor necrosis factor (TNF) and interleukin-1 beta (IL-1ß), which are both strong immune system responses.

Triggering an immune response is the purpose of an adjuvant. Thus, if used in vaccinations, VTX-294 will be an adjuvant.

The Trouble with Vaccines in Newborns

A newborn’s immune system is not the same as an adult’s, or even like that of a small child. Instead of fighting off invaders, it welcomes them. That makes sense, because the fetus is a guest in his mother’s abdomen. The fetus must be able to trust everything that comes across the placenta. Through a process that is not understood, shortly before and after birth, the immune system converts from acceptance of foreign substances to rejection of them. It takes around six months after birth for that process to be completed.

That’s why vaccines tend not to work in newborns. However, in spite of a near-complete lack of understanding about the process of immune system conversion from acceptance to rejection of foreign substances, modern medicine has decided that there’s something wrong with it. Therefore, a search has been on to try to force infants’ immune systems to develop antibodies to vaccinations.

So the discovery of VTX-294′s effects on newborns’ blood in vitro (in a laboratory, not a living being) is hailed as a breakthrough. And that it most certainly is. But that doesn’t make it a positive development.

Inflammation

Inflammation in pregnancy has been identified as a strong factor in the development of autism.^[2] TNF and IL-1ß are cytokines, and excessive cytokines—cytokine storms—have been linked to autism.^[3,4,5,6,7] What would you call the unnatural release of the cytokines TNF and IL-1ß in newborns but a cytokine storm?

Thus, this research into finding a way to activate a newborn’s immune system in a manner that is contrary to nature may be a primary triggering factor for autism!

VTX-294 and Benzene Rings

VTX-294 is a benzazepine, a chemical similar to benzodiazepines, which include diazepam and Xanax. The basis of benazapines is a combination of an azapine ring and a benzene ring.^[8]Benzene is a noted toxin, associated with cancer, along with neurological, developmental, and reproductive damage.^[9,10,11]

It’s hard to imagine that anyone would seriously consider injecting benzene, a known toxin, into newborns—until we realize that other known toxins, like mercury and formaldehyde, are already being injected with other vaccines.

Medical Hubris

The presumption of modern medical research in the assumption that there is something inherently wrong with every human baby born is pure hubris. Yet that’s precisely what’s taking place in attempts to circumvent the basic nature of a newborn’s immune system. We know from experience that there will be no tests for VTX-294′s safety. Adjuvants seem never to be tested. No matter how toxic they’re known to be, when they get added to vaccines, they automatically are defined as generally recognized as safe (GRAS).

That’s true of squalene, which has recently been shown to cause narcolepsy. It includes formaldehyde, a carcinogen, mercury, a neurotoxin, polysorbate 80, an endocrine disruptor, aluminum, a neurotoxin and possibly carcinogen. all of these are routinely used in vaccinations, which are all used in vaccines, in spite of their toxicity. When it comes to vaccines, they are termed GRAS.

If this latest adjuvant, VTX-294, gets used in vaccinations, it’s terrifying to consider the potential for harm. Will it disrupt normal immune system development? Will it cause cancer? Autism? Other neurological defects? Or create new diseases, such as macrophagic myofasciitis, which is probably induced by aluminum in vaccines?

What will it take for modern medicine to shake off the hubris-induced blinders? It seems that nothing less than the vaccine-caused devastation of every baby will stop these crimes. Or will they still try to claim that all the destroyed lives are “mere coincidence”?

Sources:

The Ultra-Potent and Selective TLR8 Agonist VTX-294 Activates Human Newborn and Adult Leukocytes: PLOS One; David J. Dowling, Zhen Tan, Zofia M. Prokopowicz, Christine D. Palmer, Maura-Ann H. Matthews, Gregory N. Dietsch, Robert M. Hershberg, Ofer Levy; doi:10.1371/journal.pone.0058164
Prenatal Inflammation Linked to Autism Risk
A proposed mechanism for autism: an aberrant neuroimmune response manifested as a psychiatric disorder.
A proposed mechanism for autism: an aberrant neuroimmune response manifested as a psychiatric disorder.
Cytokine dysregulation in autism spectrum disorders (ASD): Possible role of the environment.
Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome.
GMO-DNA Vaccines and Cytokine Storms
Benzazepine
Toxicological Review of Benzene (EPA’s report on non-cancer effects)
The toxicity of benzene and its metabolism and molecular pathology in human risk assessment
OSHA report on effects of benzene
Human Fetal Immune System Arises from Entirely Different Sources Than Adult Immune System
A Vaccine That Works in Newborns? Promising Compound May Help Protect Babies During Vulnerable Window

Tagged adjuvant vtx-294, autism, autism vaccines, benzazepine, benzene rings, conventional medicine, medical hubris, modern medicine, newborn vaccine, science, vaccine, vaccine adjuvant, vaccines, vaccines newborns, vtx-294, vtx-294 benzazepine, vtx-294 benzene, vtx-294 cytokine storm, vtx-294 il-1 beta, vtx-294 IL-1ß, vtx-294 inflammation, vtx-294 tnf, vtx-294 toxin

Month: April 2013

Vaccines’ Alum Adjuvant Path to Brain Found: Study

Reason for the Study

The Experiments

Granulomas

Movement of Alum Surrogates

Preventing FLBs from Transporting to Organs

Blood-Brain Barrier

Confirmation: FLBs Correlate with Alum Adjuvant

Effect of CCL2 Cytokines in Alum Distribution

Implications

Source:

Organic Food Is Not Discount Food

Economies of Scale

Food as a Commodity

Organic Food

More Junk Genetics Science for Autism Awareness

The Study

Why Do Such a Study?

Sources:

Oil from Petroleum Used as Vaccine Adjuvant

Antigens and Adjuvants

Animal Abuse

The Real Goal

Sources:

New Vaccine Adjuvant Targets Newborns

The Trouble with Vaccines in Newborns

Inflammation

VTX-294 and Benzene Rings

Medical Hubris

Sources: